ISSN 2398-2969      

Blood biochemistry: cortisol

Clapis

Synonym(s): Hydrocortisone


Overview

  • Major glucocorticoid regulated by ACTH and secreted by the adrenal cortex.
  • Adrenal gland disease (hyperplasia and neoplasia) in neutered rabbits is characterized by an increase in testosterone, not an increase in cortisol levels.
  • Cushing's disease (hyperadrenocorticism) is not reported in pet rabbits.
  • ACTH stimulation test not clinically used in rabbits.

Sampling

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Tests

Methodologies

  • Radioimmunoassay (RIA).
  • Fluorometric.
  • Chemiluminescence (Immulite).

Availability

  • Not widely used in rabbits.
  • Limited commercial availability.

Result Data

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Further Reading

Publications

Refereed Papers

  • Recent references from PubMed and VetMedResource.
  • Fecteau K A et al (2007) Diagnostic endocrinology: blood steroid concentrations in neutered male and female rabbits. J Exot Pet Med 16 (4), 256-259 VetMedResource.
  • Lennox A M & Chitty J (2006) Adrenal neoplasia and hyperplasia as a cause of hypertestosteronism in two rabbits. J Exot Pet Med 15 (1), 56-58 VetMedResource.

Other sources of information

  • Lennox A M & Fecteau K A (2014) Endocrine Disease. In: Manual of Rabbit Medicine. Eds: Meredith A & Lord B. BSAVA. pp 274-276.
  • Wesche P (2014) Clinical Pathology. In: Manual of Rabbit Medicine. Eds: Meredith A & Lord B. BSAVA. pp 124-137.
  • Saunders R A & Rees Davies R (2005) Differential Diagnosis. In: Notes on Rabbit Internal Medicine. Blackwell Publishing, UK. pp 1-68.

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