ISSN 2398-2969      

Alfentanil

Clapis
Contributor(s):

John Dodam


Introduction

Name

  • BANM

Class of drug

  • Analgesics (mu opioid agonist).

Description

Chemical name

  • Alfentanil hydrochloride.

Molecular formula

  • 4-anilinopipridine analogue.

Physical properties

  • Water soluble.
  • Lipid soluble
  • pKa - 6.8.

Uses

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Indications

Analgesia/profound sedation
EitherAlone for very short procedures, eg radiotherapy.
Orused in conjunction with other anesthetic protocol as part of a balanced anesthesia protocol.

  • Augments intraoperative analgesia.
  • Decreases the amount of other anesthetics that must be used. 

Ophthalmic anesthesia

  • Improved reduction in intra-ocular pressure compared to fentanyl with similar cardiac stability.
    Potent respiratory depressant. Must have facilities for tracheal intubation and IPPV.

Administration

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Pharmacokinetics

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Precautions

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Interactions

with other drugs

  • Reduces MAC of halothane by almost 50%.

Adverse Reactions

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Further Reading

Publications

Refereed papers

Other sources of information

  • Clinical Anaesthetic Pharmacology, Editors: John W Dundee, R S J Clarke, William McCaughey. Pub: Churchill Livingstone. 1991.
  • Martindale: The Extra Pharmacopoeia. The London Pharmaceutical Society. 31st Edition.
  • Based on Small Animal Formulary. Tennant, Bryn (1999) 3rd edn. Cheltenham: BSAVA. ISBN: 0 905214 44 7

RELATED CONTENT

Naloxone

Want more related items, why not
contact us

MEMBER BENEFIT

Can’t find what you’re looking for?

We have an ever growing content library on Vetlexicon so if you ever find we haven't covered something that you need please fill in the form below and let us know!

 
 
 
 

To show you are not a Bot please can you enter the number showing adjacent to this field

 Security code