ISSN 2398-2969      

Chemotherapy: safe handling

Clapis

Introduction

  • Chemotherapy Chemotherapy: general principles describes the use of cytotoxic drugs in treatment of systemic or disseminated malignant disease Cancer therapy overview.
  • Treatment of lymphoproliferative and myeloproliferative, diseases.
  • Adjunct to surgical and/or radiation treatment of primary malignant tumors with a high risk of metastasis, eg osteosarcoma, hemangiosarcoma.

General principles

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Individuals 'at risk'

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Managing chemotherapy in practice

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Managing chemotherapy at home

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Environmental safety

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Further Reading

Publications

Refereed Papers

  • Recent references from PubMed and VetMedResource.
  • Grzesiuk M, Mielecki D, Pilzys T et al (2018) How cyclophosphamide at environmentally relevant concentration influences Daphnia magna life history and its proteome. PLoS ONE 13 (4), e0195366 PubMed.
  • Ghafuria Y, Yunesian M, Nabizadeh R et al (2018) Environmental risk assessment of platinum cytotoxic drugs: a focus on toxicity characterization of hospital effluents. Int J Environ Sci Tech 15 (9), 1983-1990.
  • Parrella A, Lavorgna M, Criscuolo E et al (2014) Estrogenic activity and cytotoxicity of six anticancer drugs detected in water systems. Sci Total Environ 485, 216-222 PubMed.
  • Hayes A (2005) Safe use of anticancer chemotherapy in small animal practice. In Pract 27, 118-127 VetMedResource.

Other sources of information

  • Simon D, Mohring S, Eberle N, Nau H, Nolte I & Hamscher G (2008) Analysis of Drug Residues in Serum and Urine of Dogs Receiving Anti-Cancer Chemotherapy. In: Proceedings of the First World Veterinary Cancer Congress, Copenhagen, Denmark. pC25.
  • European College of Veterinary Internal Medicine (2006) Preventing Occupational and Environmental Exposure to Cytotoxic Drugs in Veterinary Medicine. Website: http://www.ecvim-ca.org (pdf download).
  • Health and Safety Executive (2003) Safe Handling of Cytotoxic Drugs. Website: http://www.hse.gov.uk (pdf download).
  • Health and Safety Executive (2003) Working with Substances Hazardous to Health. Website: http://www.hse.gov.uk (pdf download).
  • Control of Substances Hazardous to Health. The Control of Substances Hazardous to Health Regulations 2002 (as amended). Approved Code of Practice and Guidance L5. 5th edn. HSE Books 2005 ISBN 0 7176 2981 3
  • Management of Health and Safety at Work. Management of Health and Safety at Work Regulations 1999. Approved Code of Practice and Guidance L21. 2nd edn. HAS Books 2000 ISBN 0 7176 2488 9

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