ISSN 2398-2969      

Adenovirus infection

Clapis

Introduction

  • Adenovirus infection is rarely reported as a clinical problem in the rabbit.
  • Cause: Adenovirus.
  • Signs: profuse diarrhea, death.
  • Diagnosis: on necropsy.
  • Treatment: supportive treatment only.
  • Prognosis: guarded.

Presenting signs

  • Rabbits present with profuse diarrhea, and mortiality rates of 10-15% have been reported in a group situation.

Geographic incidence

  • One outbreak has been reported in young farmed rabbits in Hungary.
  • A serological survey of rabbits in Quebec, Canada also revealed serum-neutralizing antibodies to bovine adenovirus type 1 in rabbits in three different colonies.

Age difference

  • The reported outbreak occurred in 6-8 week old rabbits, with older rabbits thought to have developed adequate serum antibody levels.

Cost considerations

  • Group outbreaks may result in significant morbidity and mortality.

Pathogenesis

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Diagnosis

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Treatment

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Prevention

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Sequelae

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Bodon L & Prohászka L (1981) Isolation of an adenovirus from rabbits with diarrhoea. Acta Veterinaria Academiae Scientiarum Hungaricae 28 (3), 247-255 PubMed.
  • Descoteaux J P, Whissel K & Assaf R (1980) Detection of antibody titers to bovine viruses in rabbit sera. Lab Anim Sci 30 (3), 581-582 PubMed.
  • Bodon L, Prohaszka L, Adam E et al (1979) Isolation of an adenovirus from rabbits. Acta Veterinaria Academiae Scientiarum Hungaricae 27 (1/2), 73-75 VetMedResource.
  • Reddick R A & Lefkowitz S S (1969) In vitro immune responses of rabbits with persistent adenovirus type 5 infection. J Immunol 103 (4), 687-694 PubMed.

Other sources of information

  • MacLachlan N J & Dubovi E J (2011) Adenoviridae. In: Fenners Veterinary Virology. 4th ed. Academic Press, London. pp 203-212.
  • Baker D G (2003) Pathogens of Rabbits. In: Natural Pathogens of Laboratory Animals: Their Effects on Research. ASM Press, Washington DC. pp 147-148.
  • DiGiacomo R R & Mare C J (1994) Viral diseases. In: The Biology of the Laboratory Rabbit. 2nd ed. Academic Press Inc, New York. pp 188.

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