Felis ISSN 2398-2950

Biopsy: skin

Contributor(s): Rosanna Marsella, Irene Rochlitz, David Scarff

Introduction

  • Skin histopathology is a valuable aid to differential and definitive diagnosis of many skin disorders.

Uses

  • Definitive diagnosis of certain skin diseases.
  • Categorization of skin disease.

Disadvantages

  • Excisional if lesion small enough, or incisional.
  • Most animals require sedation.
  • Nasal, facial and footpad lesions: may require short-acting general anesthesia.
  • Must be obtained early in course of disease before chronic inflammatory changes occur.
  • Exercise caution if:
    • Bleeding disorders or concurrent medication, eg aspirin or anticoagulants, affecting bleeding.
    • Immunosuppressed animals: rare (may be wound healing problem).
    • Local anesthesia: injecting lignocaine Lidocaine with adrenaline near extremities and into patients with circulatory disorders (maximum 1ml of 2% lignocaine/5kg body weight).
  • Select primary lesions if possible.

Requirements

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Preparation

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Procedure

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Aftercare

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Outcomes

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Noxon J O (1995) Diagnostic procedures in feline dermatology. Vet Clin North Am Small Anim Pract 25 (4), 779-99 PubMed.

Other sources of information

  • Ihrke P J (1996) Bacterial Skin Disease in the Dog - a Guide to Canine Pyoderma. Veterinary Learning Systems. pp 59-61. (Biopsy technique with special reference to pyoderma.)
  • Ogilvie G K & Moore A S (1995) Managing the veterinary cancer patient: A practice manual. Veterinary learning systems pp6-8.
  • Moriello K A & Mason I S (1995) Eds Handbook of Small Animal Dermatology. 1st edn. Oxford: Pergamon. pp 31-33. (Step by step procedure with photographs.)
  • Muller G H et al (1995) Muller and Kirk's Small Animal Dermatology. 5th edn. Philadelphia: W B Saunders. pp 111-118. (Detailed account.)


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