Felis ISSN 2398-2950

Thyrotropin releasing hormone (TRH) stimulation test

Synonym(s): TRH stimulation test

Contributor(s): Carmel Mooney, Mark Peterson

Overview

  • In normal animals total serum thyroxine (tT4) increases >60% following administration of TRH.

Sampling

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Tests

Methodologies

  • Radioimmunoassay.

Availability

  • Most commercial laboratories.

Technique (intrinsic) limitations

  • Side-effects (salivation, vomiting, tachypnea and defecation) occur after administration of TRH.
    Side-effects resolve during the 4 hour test period so admit animals for this procedure.

Result Data

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Further Reading

Publications

Refereed papers

  • Recent references from VetMed Resource and PubMed.
  • Peterson M E, Broussard J D & Gamble D A (1994) Use of the thyrotropin-releasing hormone stimulation test to diagnose mild hyperthyroidism in cats. JVIM 4, 279-286 (good controlled study evaluating test.)
  • Sparkes A K, Jones B R, Gruffyd Jones T J & Walker M J (1991) Thyroid function in the cat - Assessment by the TRH response test and the thyrotropin stimulation test. JSAP 32, 59-63.


ADDED