Felis ISSN 2398-2950

Blood: crossmatching

Contributor(s): Sarah Gould, Severine Tasker

Overview

  • Major crossmatch detects alloantibodies in recipient plasma against donor red cells.
  • Minor crossmatch detects alloantibodies in donor plasma against recipient red cells.
  • An incompatible major crossmatch can result in an acute hemolytic transfusion reaction when donor erythrocytes are destroyed by alloantibodies in the recipient's plasma.
  • A minor crossmatch incompatibility is less likely to cause a transfusion reaction because the volume of donor plasma is small and becomes markedly diluted in the recipient.
  • Transferring incompatible blood can   →   acute transfusion reaction Anemia: transfusion indications (which can be fatal) and certainly results in shortened lifespan of transfused cells.

Sampling

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Result Data

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Further Reading

Publications

Refereed papers

  • Recent references from VetMed Resource and PubMed.
  • Forcada Y, Guitian J & Gibson G (2007) Frequencies of feline blood types at a referral hospital in the south east of England. JSAP 48, 570-573 PubMed.
  • Weinstein N M, Blais M C, Harris K, Oakley D A, Aronson L R & Giger U (2007) A newly recognized blood group in domestic shorthair cats; the Mik red cell antigen. JVIM 21, 287-292 PubMed.
  • Grot-Went & Giger U (1995) Vet Clinics N America 25(6), 1305-1322.
  • Giger U & Bucheler J (1991) Transfusion of Type-A and Type-B blood to cats. JAVMA 198, 411-418.
  • Knottenbelt C M, Addie D D, Day M J & Mackin A J (199) Determination of the prevalence of feline blood types in the UK. JSAP 40, 115-118.


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