ISSN 2398-2950      

Blood biochemistry: cholesterol

ffelis
Contributor(s):

Kathleen P Freeman


Overview

  • Major lipid in body and precursor of all steroid hormones and bile acids.
  • Obtained from diet and synthesized in liver.
  • Ancillary aid in diagnosis of several disorders but not diagnostic alone.

Sampling

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Tests

Methodologies

  • Enzymatic method most common.
  • Cholesterolesterase (hydrolyses cholesterol esters) and cholesteroloxidase are key enzymes.
  • If cholesterolesterase included, total cholesterol is measured.
  • If cholesterolesterase not included, non-esterified or 'free' cholesterol is measured.

Availability

  • Widely available.

Technique (intrinsic) limitations

  • Results only significant in conjunction with other laboratory results.

Result Data

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Further Reading

Publications

Refereed papers

  • Recent references from VetMedResource and PubMed.
  • Watson T D G & Barrie J (1993) Metabolism and hyperlipidemia in the dog and cat. A review. JSAP 34, 479.

Other sources of information

  • Ettinger S J & Feldman E C (2000) Eds. Textbook of Veterinary Internal Medicine. 5th edn. W B Saunders & Co, USA.
  • Kaneko J J, Harvey J W & Brass M L (1997) Eds. Clinical Biochemistry of Domestic Animals. 5th edn. Academic Press, USA.
  • Duncan J R, Prasse K W & Mahaffey E A (1994) Veterinary Laboratory Medicine. Clinical Pathology. 3rd edn. Iowa University Press, USA.

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