Felis ISSN 2398-2950

Xylazine

Synonym(s): Rompun, Virbaxyl, Anased, Xyla-ject

Contributor(s): Stephen Greene, Jo Murrell

Introduction

Name

  • Xylazine.

Class of drug

  • Alpha-2 adrenoceptor agonist.

Description

Storage requirements

  • Store below 30°C.

Uses

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Indications

This drug should no longer be used in cats. For a similar/alternative drug, medetomidine Medetomidine or dexmedetomidine Dexmedetomidine may be used.

Administration

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Pharmacokinetics

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Precautions

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Interactions

with other drugs

  • May get increased CNS depression if used with agents such as barbiturates, narcotics or anesthetics.
  • When combined with epinephrine may → cardiac arrhythmia.

Adverse Reactions

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Greene S A & Thurmon J C (1988) Xylazine - A review of its pharmacology and use in veterinary medicine. J Vet Pharmacol Therap 11, 295-313.

Other sources of information

  • Based on Tennant B (1999) Small Animal Formulary. 3rd edn. Cheltenham: BSAVA.

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