ISSN 2398-2950      

Sulfasalazine

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Synonym(s): Sulphasalazine


Introduction

Name

  • Sulfasalazine.

Class of drug

  • Sulfonamide/Salicylate.

Description

Molecular formula

  • 5-aminosalicylic acid (5-ASA) and sulfapyridine connected by an azo bond.

Uses

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Indications

Administration

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Pharmacokinetics

Precautions

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Interactions

with other drugs

Digoxin

  • Absorption may be decreased by sulfasalazine Digoxin.

Folic acid

  • Absorption may be decreased by sulfasalazine Folic acid.

Drugs whose action may be enhanced

  • Sulfonamides may displace highly protein bound acidic drugs such as:
  • Glipizide Glipizide and other oral hypoglycemics.
  • Methotrexate Methotrexate.
  • Phenylbutazone.
  • Phenytoin Phenytoin.
  • Salicylates.
  • Thiazide diuretics.
  • Warfarin Warfarin.

Adverse Reactions

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Further Reading

Publications

Refereed papers

Other sources of information

  • BSAVA Small Animal Formulary. Ramsey I (2017) 9th edn. Cheltenham: BSAVA.
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