ISSN 2398-2950      

Sodium bicarbonate

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Synonym(s): Bicarbonate of soda, baking soda


Introduction

Name

  • Sodium bicarbonate.

Class of drug

  • Electrolyte.
  • Alkalinizing agent.

Description

Molecular formula

  • NaHCO3

Physical properties

  • Soluble in water.

Storage requirements

  • Tablets and powder.
    • Store in air-tight containers at room temperature.
  • Injection.
    • Store at room temperature, avoid freezing.

Uses

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Indications

  • Treatment of metabolic acidosis .
  • To alkalinize urine.
  • Adjunctive therapy in the treatment of hypercalcemic or hyperkalemic crises.

Administration

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Precautions

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Interactions

with other drugs

Quinidine

  • Alkalinization of urine by sodium bicarbonate decreases the excretion of quinidine.

Sympathomimetic drugs

  • Alkalinization of urine by sodium bicarbonate decreases the excretion.

Aspirin

  • Increases the excretion of aspirin.

Phenobarbital

  • Increases the excretion of phenobarbital.

Tetracyclines (especially doxycycline)

  • Increases the excretion of tetracyclines.

Adverse Reactions

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Further Reading

Publications

Refereed papers

Other sources of information

  • BSAVA Small Animal Formulary. Ramsey I (2017) 9th edn.
  • Based on Plumb D C (2002) Veterinary Drug Handbook. 4th edn. Iowa State Press, USA.
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