ISSN 2398-2950      

Propylene glycol

ffelis
Contributor(s):

Yolande Bishop

Synonym(s): Propanediol, Methyl glycol


Introduction

Name

  • Propylene glycol.

Class of drug

  • Humectant.
  • Vehicle.
  • Solvent.
  • Glucose precursor in ruminants.
  • Lubricant

Description

Chemical name

  • 1,2-propanediol.
  • 1,2-dihydroxypropane.

Molecular formula

  • C3H8O2.

Molecular weight

  • 76.10.

Physical properties

  • Hygroscopic, viscous liquid.
  • Slightly acrid taste.
  • Melting point: -59°F.
  • Miscible with water, acetone and chloroform.

Storage requirements

  • Stable under normal conditions.
  • Will oxidize at high temperatures.

Uses

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Indications

  • Shampoos.
  • Dry skin conditions.
  • Hyperkeratotic conditions.
  • Sebaceous adenitis.

Administration

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Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Curtis C (1998) Use and abuse of topical dermatological therapy in dogs and cats. Part 1. Shampoo therapy. In Pract 20 (5) 244-251.
  • Brown J M & Kasson C W (1984) Response of dogs to subcutaneous injections of various concentrations of propylene glycol with water. Am J Vet Res 45 (1) 83-86.

Other sources of information

  • Tennant B (1999) Small Animal Formulary. 3rd edn. British Small Animal Veterinary Association. ISBN 0 905214 52 8.
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