Felis ISSN 2398-2950

Phenylpropanolamine / diphenylpyraline

Synonym(s): PPA, Propalin, Urilin

Contributor(s): Melissa Wallace, Vetstream Ltd

Introduction

Name

  • Phenylpropanolamine.

Class of drug

  • Sympathomimetic amine.

Uses

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Indications

  • Management of urinary incontinence Urinary incontinence by increasing urethral outflow resistance.

Administration

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Pharmacokinetics

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Precautions

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Interactions

with other drugs

  • Monamine oxidase (MAO) inhibitors - do not give PPA within 2 weeks of MAO inhibitors.
  • Avoid with other sympathomimetics (eg ephedrine, epinephrine Epinephrine ).
  • Avoid use with concurrent NSAIDs as may increase risk of hypertension.
  • Can cause cardiac arrhythmias if given with halogenated hydrocarbon anesthetic agents.

Adverse Reactions

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Further Reading

Publications

Refereed papers

Other sources of information

  • Plumb D C (2002) Veterinary Drug Handbook. 4th edition. Iowa State University Press, Ames, Iowa.
  • BSAVA Small Animal Formulary. Ramsey I (2017) 9th edn. 

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