ISSN 2398-2950      

Phenylephrine

ffelis
Contributor(s):

Sheryl Krohne

Vetstream Ltd


Introduction

Name

  • Phenylephrine.

Class of drug

  • Alpha-1 selective adrenergic agonist.

Uses

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Indications

  • Used in conjunction with fluid therapy, to treat hypotension secondary to drug overdose.
  • Used to slow conjunctival hemorrhage during surgery. It is used before some types of intraocular surgery to blanch conjunctival vessels.
  • When applied topically to the eye phenylephrine causes vasoconstriction and pupil dilation. It is indicated for some diagnostic eye examinations, such as diagnosing Horner's syndrome.

Administration

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Precautions

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Interactions

with other drugs

Volatile anesthetics

  • Risk of arrhythmias.

Oxytocic agents

  • Pressor effects may be enhanced leading to severe hypertension.

Adverse Reactions

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Further Reading

Publications

Refereed papers

Other sources of information

  • Ramsey I (2017) BSAVA Small Animal Formulary. 9th edn. BSAVA, UK.
  • Regnier A & Ward D (1999) Clinical Pharmacology and Therapeutics. In: Veterinary Ophthalmology. 3rd edn. Ed K Gelatt. Lippincott, Williams and Wilkins, USA.
  • Plumb D (1999) Veterinary Drug Handbook. 3rd edn. Ames: Iowa State University Press.
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