ISSN 2398-2950      

Hydromorphone

ffelis

Introduction

Name

  • Hydromorphone hydrochloride.

Class of drug

Description

Molecular formula

  • 4,5±-epoxy-3-hydroxy-17-methylmorphinan-6-one hydrochloride

Molecular weight

  • 321.80

Physical properties

  • White powder.
  • Freely soluble in water.
  • Semi-synthetic phenanthrene alkaloid of opium.

Storage requirements

  • Store at 15-30°C.
  • Protect from light.

Uses

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Indications

  • Use as an opioid analgesic.
  • A cost-effective alternative to oxymorphone.
  • For the relief of pain.
  • Can be used pre-emptively for elective surgical procedures.
  • Can be used to relieve pain from trauma.
  • Has also been used to provide longer-term pain relief, eg that caused by osteosarcoma.

Administration

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Pharmacokinetics

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Precautions

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Interactions

with other drugs

  • Can cause profound sedation when combined with acepromazine Acepromazine maleate  , alpha2-agonists (xylazine Xylazine, medetomidine Medetomidine) and benzodiazepines.
  • Hydromorphone may reduce the induction dose of injectable anesthetic agents and lower the dose of inhalant agents required for maintenance of anesthesia.

Adverse Reactions

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Pascoe PJ (2000) Opioid analgesics. Vet Clin North Am Small Anim Pract 30( 4), 757-772.
  • Pettifer G & Dyson D (2000) Hydromorphone: a cost-effective alternative to the use of oxymorphone. Can Vet J 41 (2), 135-137
MEMBER BENEFIT

Can’t find what you’re looking for?

We have an ever growing content library on Vetlexicon so if you ever find we haven't covered something that you need please fill in the form below and let us know!

 
 
 
 

To show you are not a Bot please can you enter the number showing adjacent to this field

 Security code