ISSN 2398-2950      

Heparin

ffelis
Contributor(s):

Mark Rishniw


Introduction

Name

  • Heparin.

Class of drug

  • Anticoagulant.

Description

Physical properties

  • Heterogeneous group of glycosaminoglycans.

Storage requirements

  • Room temperature.

Uses

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Indications

  • Given to promote anticoagulation.
  • Primary uses in small animal medicine include the treatment of disseminated intravascular coagulation (DIC) and thromboembolic disease , and the maintenance of IV catheter patency.
    Use in DIC is controversial and information on efficacy is lacking.
  • Feline aortic thromboembolism - efficacy questionable.

Administration

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Pharmacokinetics

Precautions

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Interactions

with other drugs

ACTH
  • May antagonize the actions of ACTH.

Corticosteroids

  • May antagonize the actions of corticosteroids.

Insulin

  • May antagonize the actions of insulin.

Diazepam

  • May increase plasma levels of diazepam.

Antihistamines, digoxin and tetracyclines

  • The actions of heparin may be partially counteracted.

Adverse Reactions

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Further Reading

Publications

Refereed papers

Other sources of information

  • Based on Small Animal Formulary. Tennant Bryn (1999) 3rd edn. BSAVA, UK.
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