Felis ISSN 2398-2950

Glipizide

Synonym(s): Glibenase, Minodiab

Contributor(s): Vetstream Ltd

Introduction

Name

  • Glipizide.

Class of drug

  • Sulfonylurea.

Description

Physical properties

  • White powder.

Storage requirements

  • Store in light-tight containers.

Uses

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Indications

  • Management of type-II or non-insulin-dependent diabetes mellitus (NIDDM)   Diabetes mellitus  where there is some residual insulin production.
  • In these cases it may be effective alone or administered with insulin to reduce insulin requirements.
  • Glipizide is ineffective when there is an absolute insulin deficiency (IDDM) or when insulin resistance is present.

Administration

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Pharmacokinetics

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Precautions

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Interactions

with other drugs

  • The effects of glipizide may be enhanced by ACE inhibitors, NSAIDs, chloramphenicol, potentiated sulfonamides and fluoroquinolones.
  • Glipizide may prolong the action of barbiturates.
  • Probencid, cimetidine or monoaminoxidase inhibitors may increase the hypoglycemic effects of glipizide.

Adverse Reactions

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Hoenig M, Hall G, Ferguson D et al (2000) A feline model of experimentally induced islet amyloidosis. Am J Pathol 157, 2143-2150.

Other sources of information

  • BSAVA Small Animal Formulary. Ramsey I (2017) 9th edn. Cheltenham: BSAVA.

ADDED