ISSN 2398-2950      

Cefalexin

ffelis
Contributor(s):

Stephen Barr

Vetstream Ltd

Synonym(s): Cephalexin


Introduction

Name

  • Cefalexin.

Class of drug

  • 1st generation cephalosporin antibiotic.
  • Member of beta-lactam group.

Description

Chemical name

  • [6R-[6-alpha,7-beta(R*]]-7-(aminophenylacetyl)amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid.

Molecular formula

  • C16H17N3O4S.

Physical properties

  • Oily suspension.
  • Granules.
  • Tablets.

Storage requirements

  • <25°C.
  • Protect from light.
  • Refrigeration preferable.

Uses

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Indications

Administration

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Precautions

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Interactions

with other drugs

Bacteriostatic antibiotics

  • The bactericidal activity of cephalosporins may be affected by the concomitant use of bacteriostatic agents, eg erythromycin Erythromycin , tetracycline Tetracycline.

Amphotericin and loop diuretics

Probenicid

  • Probenecid reduces the excretion of cephalosporins.

Adverse Reactions

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Further Reading

Publications

Refereed papers

Other sources of information

  • Based on Small Animal Formulary. Tennant B (1999) 3rd edn. BSAVA, UK.
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