Felis ISSN 2398-2950
Amoxicillin
Synonym(s): Amoxycillin
Contributor(s): Lauren Trepanier
Introduction
Name
Class of drug
Description
Chemical name
- 6[D](-)-a-amino-p-hydroxyphenylacetamido] penicillanic acid.
Physical properties
- Acid-stable, beta-lactamase-susceptible.
Uses
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Indications
- Active against certain gram-positive and negative organisms.
- Not active against those that produce penicillinases, eg someE. coli Escherichia coli andStaphylococcus aureus Staphylococcus spp .
- The more difficult gram-negative organisms (Pseudomonas spp Pseudomonas spp andKlebsiella spp) are usually resistant.
Administration
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Pharmocokinetics
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Precautions
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Interactions
with other drugs
Probenecid
- Will decrease the renal tubular secretion of penicillin antibiotics Penicillamine and thus prolong their blood levels.
Aminoglycosides
- Do not mix in the same syringe as aminoglycosides.
Adverse Reactions
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Further Reading
Publications
Other sources of information
- Based onSmall Animal Formulary.Tennant, Bryn (1999) 3rd edn. Cheltenham: BSAVA.