ISSN 2398-2950      

Amitryptiline

ffelis

Introduction

Name

  • Amitryptiline.

Class of drug

  • Tricyclic antidepressant.

Description

Physical properties

  • Soluble in water and alcohol.
  • Bitter taste.

Uses

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Indications

Administration

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Pharmacokinetics

Precautions

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Interactions

with other drugs

Anesthetics and antidysrhythmics

  • Increased risk of dysrhythmias.

Anti-epileptics

  • Antagonizes the effects of anti-epileptics.
  • Cimetidine   →   reduces metabolism of amitriptiline   →   increased concentration of amitriptiline.

Sedatives

  • Increases sedative effect if used with other sedative drugs.

Adverse Reactions

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Scott D W & Miller W H Jr (1993) Nonsteroidal anti-inflammatory agents in the management of canine allergic pruritus. J S Afr Vet Assoc 64 (1), 52-56.
  • Miller W H Jr, Scott D W & Wellington J R (1992) Nonsteroidal management of canine pruritus with amitriptiline. Cornell Vet 82 (1), 53-57.
  • Friehe H & Fontaine R (1978) Toxicology of amitriptilinoxide. Arzneimittelforschung 28 (10b), 1898-1907.

Other sources of information

  • Based on Tennant B (1999) Small Animal Formulary. 3rd edn. BSAVA, UK.
  • Plumb D Veterinary Drug handbook. 3rd edn. pp 34-36.
MEMBER BENEFIT

Can’t find what you’re looking for?

We have an ever growing content library on Vetlexicon so if you ever find we haven't covered something that you need please fill in the form below and let us know!