Felis ISSN 2398-2950

Renal function assessment

Contributor(s): David Godfrey, Yvonne McGrotty, Roger Powell

Introduction

  • Accurate clinical evaluation of renal function can be accomplished by a series of diagnostic procedures.
  • Examination of coincident and sometimes serial urinary and blood samples is essential in this diagnostic process. 
  • Normal urine production is the total effect of glomerular and tubular function.
  • Functional tests will be discussed under glomerular and tubular function, although there is some overlap, since disease in one unit of this closely linked system ultimately affects the other. 

Is the damage affecting the tubules or glomerulus?

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Assessment of tubular function

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Ernst R et al (2018) Comparative performance of IDEXX SDMA Test and the DLD SDMA ELISA for the measurement of SDMA in canine and feline serum. PLoS ONE 13(10), e0205030 PubMed
  • Peterson M E, Varela F V, Rishniw M, Polzin D J (2018) Evaluation of Serum Symmetric Dimethylarginine Concentration as a Marker for Masked Chronic Kidney Disease in Cats With Hyperthyroidism. JVIM 32(1), 295-304 PubMed
  • Hokamp J A, Nabity M B (2016) Renal biomarkers in domestic species. Vet Clin Pathol 45(1), 28-56 PubMed.
  • Hall J A et al (2014) Comparison of serum concentrations of symmetric dimethylarginine and creatinine as kidney function biomarkers in healthy geriatric cats fed reduced protein foods enriched with fish oil, L-carnitine, and medium-chain triglycerides. Vet J 202(3), 588-596 PubMed.


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