ISSN 2398-2950      

Hyperthyroidism: radio-iodine treatment

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Introduction

  • Best method of treating human and feline hyperthyroidism Hyperthyroidism.
  • Fewest complications and highest success rate (94-98%).
  • Uses a radioactive isotope of iodine - iodine-131 (I-131).
  • Suitable for cats that have had previous therapy (thyroidectomy Thyroidectomy, methimazole Methimazole).
  • High-dose radio-iodine treatment has been used successfully to treat cats with thyroid carcinoma Thyroid gland: neoplasia.
  • Main contra-indication is the presence of intercurrent disease that requires daily monitoring/treatment.
  • Licensed facilities also offering radio-iodine treatment currently available in the UK are the Animal Health Trust, the University Veterinary Schools at Bristol, Edinburgh, Glasgow, London and Royal Veterinary College, Barton Veterinary Hospital, Bishopton Veterinary Group, Pride Veterinary Centre, Rowe Veterinary Referrals, and The Hyperthyroid Cat Centre. Please contact these centers for relevant details.
  • For centers that offer radiotherapy treatment for feline hyperthyroidism in the USA, please visit:  http://www.veterinarypartner.com and search for radiotherapy facilities.

Cats with pre-existing renal disease may deteriorate after treatment for hyperthyroidism by any method. Radio-iodine offers no significant advantage over medical or surgical therapy in this respect.Print off the owner factsheet Cancer treatment - radio-iodine treatment for thyroid cancer  Cancer treatment - radio-iodine treatment for thyroid cancer to give to your client.

Principles

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Radiation safety

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Indications / contraindications

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Method

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Efficacy

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Harvey A M, Hibbert A, Barrett E L et al (2009) Scintigraphic findings in 120 hyperthyroid cats. J Feline Med Surg 11 (2), 96-106 PubMed.
  • Hibbert A, Gruffydd-Jones T, Barrett E L et al (2009) Feline thyroid carcinoma: diagnosis and response to high-dose radioactive iodine treatment. J Feline Med Surg 11 (2), 116-124 PubMed.
  • Nykamp S G, Dykes N L, Zarfoss M K et al (2005) Association of the risk of development of hypothyroidism after iodine 131 treatment with the pretreatment pattern of sodium pertechnetate Tc 99m uptake in the thyroid gland in cats with hyperthyroidism: 165 cases (1990-2002). JAVMA 226 (10), 1671-1675 PubMed.
  • Chun R, Garrett L D, Sargeant J et al (2002) Predictors of response to radioiodine therapy in hyperthyroid cats. Vet Radiol Ultrasound 43 (6), 587-591 PubMed.
  • Peterson M E, Becker D V (1995) Radioiodine treatment of 524 cats with hyperthyroidism. JAVMA 207 (11), 1422-1428 PubMed.
  • Slater M R, Komkor A, Robinson L E et al (1994) Long-term follow-up of hyperthyroid cats treated with iodine-131. J Vet Radiol Ultrasound 35 (3), 204-209 VetMedResource.

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