Felis ISSN 2398-2950

Skin: papilloma

Contributor(s): John Munday, Irene Rochlitz, David Scarff

Introduction

  • Only 6 reported cases of viral papillomas in cats.
  • Lesions were benign in all cases.
    Do not confuse papillomas with feline viral plaques.
  • Middle aged to old cats.
  • Cause: oral papillomas associated with Felis catus papillomavirus type 1.
  • Cause of cutaneous papillomas unknown.
  • Signs: multiple masses on ventral surface of tongue or solitary mass maybe most common around head.
  • Diagnosis: clinical appearance for oral papillomas; however, histopathology of biopsy required for definitive diagnosis.
  • Treatment: probably will resolve spontaneously.
  • Prognosis: limited data suggests excellent prognosis.

Pathogenesis

Pathophysiology

  • Papillomavirus infects basal cells.
  • Infection results in marked epithelial hyperplasia.
  • Thickened epithelium becomes folded resulting in an exophytic lesion.
  • Spontaneous regression occurs when body mounts cell-mediated immune response against infected cells.
  • In contrast to viral plaques Skin: cutaneous viral plaques, there is no evidence that papillomas predispose to neoplasia in cats.

Diagnosis

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Treatment

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Outcomes

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Munday J S (2014) Papillomaviruses in felids. Vet J 199 (3), 340-347 PubMed
  • Munday J S, Fairley R A, Mills H et al (2014) Oral papillomas associated with Felis catus papillomavirus type 1 in two domestic cats. Vet Pathol 52 (6), 1187-90 PubMed.
  • Egberink H, Thiry E, Möstl K et al (2013) Feline Viral Papillomatosis: ABCD guidelines on prevention and management. J Feline Med Surg 15 (7), 560-562 PubMed.
  • Munday J S, Hanlon E M, Howe L et al (2007) Feline cutaneous viral papilloma associated with human papillomavirus type 9. Vet Pathol 44 (6), 924-927 PubMed.


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