Felis ISSN 2398-2950

Skin: neoplasia

Contributor(s): Laura Garrett, Rosanna Marsella, Susan North, David Scarff

Introduction

  • Second most common site for feline tumors.
  • Skin tumors in cats make up 20-30% of all tumors.
  • Less common than in dogs.
  • Fewer different types occur but higher percentage is malignant. Malignant skin tumors in cats are reported to be three times more common than benign tumors.
  • Relative frequency of various skin tumors has been reported to be changing with fibrosarcoma becoming more common than epithelial skin tumors.
    Follow the diagnostic algorithm for the investigation of a Feline cutaneous mass Feline cutaneous mass.

Pathogenesis

Etiology

Specific

  • Squamous cell carcinoma - white hair on face, common sites pinna  Squamous cell carcinoma: pinna 01 , nasal planum  Squamous cell carcinoma: nasal planum - pre-radiotherapy .
  • Fibrosarcoma - commonly at injection sites.

Pathophysiology

  • Primary mass may cause problems if very large or becomes ulcerated, secondarily infected or is at an irritating site, eg eyelid Eyelid and conjunctiva: neoplasia.
  • If malignant, may spread to local lymph nodes and/or distant sites.
  • Primary mass may cause problems, ie impair limb movement if very large or becomes ulcerated, secondarily infected or is at an irritating site, eg eyelid  Squamous cell carcinoma: eyelid 01 - tabby  white DSH 12 years . May be erosive or disfiguring.
  • If malignant, may spread to local lymph nodes and/or distant sites.

Diagnosis

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Treatment

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Prevention

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Outcomes

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Miller M A, Nelson S L, Turk J R et al (1991) Cutaneous neoplasia in 340 cats. Vet Pathol 28 (5), 389-395 PubMed.
  • Bostock D E (1986) Neoplasms of the skin and subcutaneous tissues in dogs and cats. Brit Vet J 142 (1), 1-19 PubMed.
  • Susaneck S J (1983) Feline skin tumors. Compend Contin Educ 5 (4),  251-258 VetMedResource.
  • Macy D W & Reynolds H A (1981) The incidence, characteristics and clinical management of skin tumors of cats. JAAHA 17 (6), 1026-1034 VetMedResource.
  • Scott D W (1980) Feline Dermatology 1900-1978: a monograph. JAAHA 16 (3), 331-459 VetMedResource.

Other sources of information

  • Guaguere E & Prelaud P (1999) A practical guide to feline dermatology.Merial.
  • Carpenter J L, Andrews L K and Holzworth J (1987) Tumors and Tumor-like lesions. In: Diseases of the Cat. Medicine and Surgery. Ed J Holzworth. Philadelphia: W B Saunders Co. pp 406-596.
  • Vail D M and Withrow S J (1996) Tumors of the skin and subcutaneous tissues. In: Small Animal Clinical Oncology. Eds S J Withrow and E G MacEwen. 2nd edition. Philadelphia: W B Saunders Co. pp 167-191.


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