ISSN 2398-2950      

Skin: lymphocytic neoplasia

ffelis

Synonym(s): Lymphosarcoma, lymphoma, mycosis fungoides, Sezary syndrome


Introduction

  • Uncommon, malignant lymphoid proliferations in dermis, sometimes with epitheliotropism.
  • Early stages may appear inflammatory, plaque-like or alopecic.
  • Later, nodular, sometimes oral.

Pathogenesis

Etiology

Pathophysiology

  • Primary cutaneous lymphosarcoma originates in the skin.
  • Secondary cutaneous lymphosarcoma arises by dissemination from another site .
  • Primary cutaneous lymphosarcoma includes:

Non-epitheliotropic lymphosarcoma

  • A tumor of B-lymphocytes or T-lymphocytes, causing generalized, multifocal or occasionally solitary dermal or subcutaneous nodules.

Epitheliotropic lymphosarcoma

  • Very rare tumor of T-lymphocytes includes:
    • Mycosis fungoides (a primary cutaneous lymphoma).
    • Sezary syndrome (a leukemic variant of mycosis fungoides).

Timecourse

  • Weeks to months.

Diagnosis

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Treatment

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Outcomes

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Tobey J C, Houston D M, Breur G J et al (1994) Cutaneous T-cell lymphoma in a cat. JAVMA 204 (4), 606-9 PubMed.
  • Schick R O, Murphy G F, Goldschmidt M H (1993) Cutaneous lymphosarcoma and leukaemia in a cat. JAVMA 203 (8), 1155-58 VetMedResource.
  • Wellman M  L, Hammer A S, DiBartola S P et al (1992) Lymphoma involving large granular lymphocytes in cats - 11 cases (1982-1991). JAVMA 201 (8), 1265-9 PubMed.

Can’t find what you’re looking for?

We have an ever growing content library on Vetlexicon so if you ever find we haven't covered something that you need please fill in the form below and let us know!

 
 
 
 

To show you are not a Bot please can you enter the number showing adjacent to this field

 Security code