Felis ISSN 2398-2950

Sarcoma

Contributor(s): Laura Garrett, Susan North, David Scarff, Jane Dobson

Introduction

  • Group of tumors derived from mesenchymal tissues.
  • Fibrosarcoma is most common in cat.
  • Also includes:
    • Spindle cell sarcoma.
    • Undifferentiated sarcoma.
    • Myxosarcoma.
    • Rhabdomyosarcoma.
  • Signs: solitary, soft tissue mass.
  • Diagnosis: biopsy and histopathology.
  • Treatment: surgery (+/- radiation).
  • Prognosis: good if completely excised.
  • The following section refers to the typical soft tissue and fibrosarcomas that affect older cats. The more aggressive variant that may be associated with vaccination or other injections (Feline injection site sarcoma (FISS)) is covered separately Feline injection-site associated sarcoma.

Pathogenesis

Etiology

  • Mainly unknown.
  • Possible association with chronic inflammation, eg ocular sarcoma associated with trauma to eye.

Pathophysiology

  • Usually slow growing connective tissue tumors, slow to metastasize to lungs or other sites (usually hematogenous spread).
  • Slow growing mass in dermis/subcutis - local problem only - low rate of metastasis to lungs, other sites.

Diagnosis

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Treatment

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Outcomes

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Miller M A, Nelson S L, Turk J R et al (1991) Cutaneous neoplasia in 340 cats. Veterinary Pathology 28 (5), 389-395 PubMed.
  • Dubielzig R R, Everitt J, Shadduck J A et al (1990) Clinical and morphologic features of post-traumatic ocular sarcomas in cats. Veterinary Pathology 27 (1), 62-65 PubMed.
  • Macy D W & Reynolds H A (1981) The incidence, characteristics and clinical management of skin tumors of cats. JAAHA 17 (6), 1026-1034 VetMedResource.

Other sources of information

  • Langley-Hobbs S J, Demetriou J L & Ladlow J F (eds) (2014) Feline Soft Tissue and General Surgery. Elsevier.
  • Carpenter J L, Andrews L K & Holzworth J (1987) Fibroma and Fibrosarcoma. In: Diseases of the Cat. Medicine and Surgery. Ed J Holzworth. Philadelphia: W B Saunders Co. pp 417-421.


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