Felis ISSN 2398-2950

Primary seborrhea

Synonym(s): Keratinization defect

Contributor(s): Catherine Fraser, Rosanna Marsella, Ian Mason, David Godfrey

Introduction

  • Rare, inherited disorder of keratinization or cornification.
  • Signs: scaly skin, often greasy, often malodorous, comedo formation.
  • Prognosis: incurable, depends on severity.

Pathogenesis

Etiology

  • Inherited condition in Persian cats (?autosomal recessive). Any sex and color can be affected.

Pathophysiology

  • Genetically determined trait, causing uncharacterized cell defect   →   excessive epidermal cell turnover.

Timecourse

  • Present at birth.
  • Lifelong.
  • Worsens over time.

Diagnosis

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Treatment

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Prevention

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Outcomes

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Paradis M & Scott D W (1990) Hereditary primary seborrhea oleosa in Persian Cats. Feline Practice 19, 17.

Other sources of information

  • Miller W H, Griffin C E & Campbell K L (2013) Small Animal Dermatology. Philadelphia, W B Saunders. pp 576-567. ISBN 978-1-4160-0028-0 (the standard dermatology text).
  • Kwochka K W (1993) Keratinization abnormalities - understanding the mechanism of scale formation. In: Advances in Veterinary Dermatology. Volume 2. Eds: P J Ihrke et al. New York: Pergamon Press. pp 91.


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