Felis ISSN 2398-2950

Nocardiosis

Contributor(s): Stephen Barr, Danielle Gunn-Moore, Kim Willoughby

Introduction

  • Relatively rare bacterial disease of cats.
  • Cause: infection with Nocardia spp (usually Nocardia asteroides).
  • Signs: vague signs of illness, dyspnea.
  • Diagnosis: pyogranulomatous lesions detected, bacterial culture.
  • Treatment: surgical drainage (or excision), antibiotic therapy.
  • Prognosis: variable to poor (depending on underlying cause).

Pathogenesis

Predisposing factors

General

Pathophysiology

  • Organism can survive for a long time in the environment.
  • It is a ubiquitous soil saprophyte.
  • Present in large amount in soil.
  • Infects wounds via soil contamination or inhaled to produce respiratory disease.
  • Disease develops if large numbers of organisms are present and there is some immunosuppression in host.
  • Cause granulomatous reactions often localized in thoracic cavity with exudate occasionally containing sulfur granules.
  • Not transmissible from infected animals but other susceptible animals could potentially be infected from the same source.

Diagnosis

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Treatment

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Outcomes

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Hirsch D C & Jang S S (1999) Antimicrobial susceptibility of Nocardia nova isolated from five cats with nocardiosis. JAVMA 215 (6), 815-817 PubMed.
  • Mealey K L, Willard M D, Nagode L A et al (1999) Hypercalcaemia associated with granulomatous disease in a cat. JAVMA 215 (7), 959-962 VetMedResource.
  • Tigner S L & Anstey S I (1996) Nocardial peritonitis in a cat. Aust Vet J 74 (6), 430-432 PubMed.
  • Davenport D J & Johnson G C (1986) Cutaneous nocardiosis in a cat. J Am Vet Med Assoc 188 (7), 728-729 PubMed.

Other sources of information

  • Edwards D F (1998) Nocardiosis. In: Infectious diseases of the Dog and Cat. 2nd Edn. Ed. Greene C E. WB Saunders Co. pp 308-312.


ADDED