ISSN 2398-2950      

Neoplasia: ceruminous gland

ffelis

Synonym(s): Ceruminous gland adenoma, ceruminous gland adenocarcinoma, ceruminous gland carcinoma, apocrine adenoma, aprocrine adenocarcinoma, apocrine carcinoma


Introduction

  • Neoplasia of the apocrine sweat glands found in the external ear canal.
  • Malignant in about 50% of cases.
  • Affects older cats most commonly.
  • Signs: include aural discharge, masses, and pruritus. It is a cause of recurrent unilateral otitis externa in the older cat.
  • Diagnosis: appearance, histopathology.
  • Treatment: consists of surgery possibly followed by radiation therapy.
  • Prognosis: recurrences are common without removal of the ear canal.

Pathogenesis

Etiology

  • Unknown, tumors may develop without obvious causation or may be related to presence of chronic otitis.

Pathophysiology

  • It is proposed in some cases that chronic irritation associated with otitis externa  →  dysplastic and hyperplastic ceruminous glands (ceruminous cystomatosis Ear: ceruminous cystomatosis)   →  progress to adenomas or adenocarcinoma.
  • Adenocarcinomas are usually unilateral but the underlying irritation or ceruminous cystomatosis is usually bilateral.

Diagnosis

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Treatment

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Outcomes

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Bacon N J, Gilbert R L, Bostock D E et al (2003) Total ear canal ablation in the cat: indications, morbidity and long-term survival. JSAP 44 (10), 430-434 PubMed.
  • London C A, Dubilzeig R R, Vail D M et al (1996) Evaluation of dogs and cats with tumours of the ear canal: 145 cases (1978-1992). JAVMA 208 (9), 1413-1418 PubMed.
  • Moisan P G & Watson G L (1996) Ceruminous gland tumours in dogs and cats: a review of 124 cases. JAAHA 32 (5), 448-452 PubMed.
  • Marino D et al (1994) Results of surgery and long-term follow up in cats with ceruminous gland adenocarcinoma. JAAHA 30, 54-58.
  • Théon A P, Barthez P Y, Madewell B R et al (1994) Radiation therapy of ceruminous gland carcinomas in dogs and cats. JAVMA 205 (4), 566-569 PubMed.

Other sources of information

  • Miller W H, Griffin C E & Campbell K L (2013) Diseases of eyelids, claws, anal sacs, and ears. In: Muller and Kirk's Small Animal Dermatology. 7th edn, Elsevier, St Louis. p 752.

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