Felis ISSN 2398-2950

Indolent ulcer

Synonym(s): Eosinophilic ulcer, rodent ulcer

Contributor(s): Dennis E Brooks, David Scarff, David Godfrey

Introduction

  • Cause: various hypersensitivity disorders or heritable.
  • Signs: ulcerated lesion on the upper lip.
  • Diagnosis: history and clinical signs, and trial treatments for the underlying causes.
  • Treatment: identification and correction of underlying cause. Symptomatic.
  • Prognosis: excellent if underlying disorder is identified and treated.

Pathogenesis

Etiology

Hypersensitivity

Ectoparasites

Infection

Other causes

  • Genetic factors.

Pathophysiology

  • Cause is unclear but thought to be a hypersensitivity reaction pattern particularly to fleas.
  • Unknown.

Diagnosis

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Treatment

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Outcomes

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Wildermuth B E, Griffin C E & Rosenkrantz W S (2011) Response of feline eosinophilic plaques and lip ulcers to amoxicillin trihydrate-clavulanate potassium therapy: a randomized, double-blind placebo-controlled prospective study. Vet Dermatol 23 (2), 110-8 PubMed.
  • Bardag√≠ M, Fondati A, Fondevila D et al (2003) Ultrastructural study of cutaneous lesions in feline eosinoophilic granuloma complex. Vet Dermatol 14 (6), 297-303 PubMed.
  • Columbini S, Hodgin E C, Foil C S et al (2001) Induction of feline flea allergy dermatitis and the incidence and histopathological characteristics of concurrent indolent lip ulcers. Vet Dermatol 12 (3), 155-161 PubMed.
  • Fondati A, Fondevila D & Ferrer L (2001) Histopathological study of feline eosinophilic dermatoses. Vet Dermatol 12 (6), 333-338 PubMed.
  • von Tscharner C & Bigler B (1989) The eosinophilic granuloma complex. JSAP 30 (4), 228-9 VetMedResource.

Other sources of information

  • Miller W H, Griffin C E & Campbell K L (2013) Feline eosinophilic granuloma complex. In: Muller and Kirk's Small Animal Dermatology. Miller  WH, Griffin C E & Campbell K L (eds). Elsevier Mosby, St Louis, Missouri, pp 714.
  • Gross T et al (2005) Ulcerative and crusting dermatoses of the epidermis. In: Skin Diseases of the Dog and Cat, Clinical and Histopathologic Diagnosis. Ames Blackwell Science, pp 116.
  • Rosenkrantz W S (1992) Feline eosinophilic granuloma complex. In: Griffin C E, Kwochka K W, MacDonald J M (eds) Current Veterinary Dermatology: the Science and Art of Therapy. Mosby Year Book, St Louis, pp 319.


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