ISSN 2398-2950      

Idiopathic polymyositis

ffelis

Synonym(s): Immune-mediated polymyositis


Introduction

  • Cause: suspected immune-mediated.
  • Signs: weakness, reluctance to jump, stiff-stilted gait, muscle atrophy.
  • Diagnosis: elevated CK, muscle biopsy, ruling-out infectious causes.
  • Treatment: immune-suppressive therapy with prednisolone.
  • Prognosis: fair although relapses may occur.
Print off the owner factsheet on Myositis Myositis to give to your client.

Pathogenesis

Etiology

  • Cause unknown, although responsiveness of disease to immunosuppressive therapy suggests immune-mediated pathogenesis.
  •  Can be paraneoplastic syndrome secondary to tumor such as thymoma Thymoma.

Predisposing factors

General

  • None identified.

Pathophysiology

  • Polymyositis suspected to be autoimmune in origin.
  • Rarely can be secondary to thymoma.

Timecourse

  • Timecourse of disease extremely variable depending on predominant clinical signs.

Diagnosis

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Treatment

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Outcomes

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Ginman A A, Kline K L, Shelton G D (2009) Severe polymyositis and neuritis in a cat. J Am Vet Med Assoc 235 (2), 172-175 PubMed.
  • Sura R, Hinckley L S, Risatti G R et al (2008) Fatal necrotising fasciitis and myositis in a cat associated with Streptococcus canis. Vet Rec 162 (14), 450-453 PubMed.
  • Dickinson P J, LeCouteur R A (2004) Feline neuromuscular disorders. Vet Clin North Am Small Anim Pract 34 (6), 1307-1359 PubMed.
  • Podell M (2002) Inflammatory myopathies. Vet Clin North Am: Sm Anim Pract 32 (1), 147-167 PubMed.

Can’t find what you’re looking for?

We have an ever growing content library on Vetlexicon so if you ever find we haven't covered something that you need please fill in the form below and let us know!