ISSN 2398-2950      

Hypotrichosis with thymic aplasia

ffelis
Contributor(s):

Michael Day


Introduction

  • Cause: uncommon congenital immunodeficiency disease of Birman kittens.
  • Signs: born without hair coat or thymus.
  • Prognosis: die at birth or by 13 weeks.

Pathogenesis

Pathophysiology

  • Pedigree analysis suggests autosomal recessive mode of inheritance, although proportion of affected kittens is greater than expected.
  • Failure of ectodermal (hypotrichosis) and entodermal (thymic aplasia) development.

Diagnosis

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Prevention

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Casal M L, Straumann U, Sigg C et al (1994) Congenital hypotrichosis with thymic aplasia in nine Birman kittens. JAAHA 30 (6), 600-02 VetMedResource.

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