ISSN 2398-2950      

Hypoparathyroidism

ffelis
Contributor(s):

Introduction

  • Relatively rare as primary disorder.
  • Characterized by hypocalcemia + hypophosphatemia and either transient or permanent PTH insufficiency.
  • Cause:most commonly iatrogenic (following bilateral thyroidectomy).
  • Signs: muscle twitching, weakness or tetanus and convulsions.
  • Diagnosis; laboratory data.
  • Treatment; calcium and Vit D supplementation.
  • Prognosis: good if early recognition and treatment.

Pathogenesis

Etiology

  • Agenesis of parathyroid glands.
  • Complication of thyroidectomy: removal of or damage to parathyroids.
    One parathyroid gland is sufficient to prevent occurrence of tetany.
  • Atrophy of parathyroid glands.
  • Idiopathic: rare (may be associated hypothyroidism).

Pathophysiology

  • Decreased serum ionized calcium   →   increased neuromuscular irritability   →   tetany and convulsions.

Timecourse

  • Within days or months of thyroidectomy.
  • May be temporary or permanent.

Diagnosis

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Treatment

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Outcomes

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Ruopp J L (2001) Primary hypoparathyroidism in a cat complicated by suspect iatrogenic calcinosis cutis. J Am Anim Hosp Assoc 37 (4), 370-373 PubMed.

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