Felis ISSN 2398-2950

Eyelid and conjunctiva: neoplasia

Contributor(s): Dennis E Brooks, Irene Rochlitz, David L Williams, James Oliver

Introduction

  • Cause: usually spontaneous, exposure to high levels of UV radiation.
  • Signs: mass, ocular discharge, 'red eye', ocular discomfort, periocular swelling.
  • Diagnosis: clinical examination, cytology, histopathology.
  • Treatment: surgical excision, radiotherapy, chemotherapy, plesiotherapy.
  • Prognosis: guarded, often malignant.

Pathogenesis

Etiology

Predisposing factors

General

  • Older cats.
  • Unpigmented eyelids.
  • Sunny climates.

Specific

  • High levels of UVB can induce malignant transformation of squamous epithelial cells.

Pathophysiology

  • High levels of UVB can induce malignant transformation of squamous epithelial cells.

Timecourse

  • Weeks to months.

Diagnosis

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Treatment

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Prevention

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Outcomes

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Murphy S (2013) Cutaneous squamous cell carcinoma in the cat: current understanding and treatment approaches. J Feline Med Surg 15 (5), 401-407 PubMed.
  • Montgomery K W, van der Woerdt A, Aquino S M et al (2010) Periocular cutaneous mast cell tumors in cats: evaluation of surgical excision (33 cases). Vet Ophthalmol 13 (1), 26-30 PubMed.
  • Schobert C S, Labelle P, Dubielzig R R (2010) Feline conjunctival melanoma: histopathological characteristics and clinical outcomesVet Ophthalmol 13 (1), 43-46 PubMed.
  • Newkirk K M, Rohrbach B W (2009) A retrospective study of eyelid tumors from 43 cats. Vet Pathol 46 (5), 916-927 PubMed.
  • Aquino S M (2007) Management of eyelid neoplasms in the dog and cat. Clinical techniques in Small Animal Practice 22 (2), 46-54 PubMed.

Other sources of information

  • Mitchell N & Oliver J (2015) Feline Ophthalmology - The Manual. Servet. ISBN 978-84-16315-11-6.
  • Gould D & McLellan G (2014) BSAVA Manual of Small Animal Ophthalmology. 3rd edn. British Small Animal Veterinary Association.


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