Felis ISSN 2398-2950
Eyelid and conjunctiva: neoplasia
Contributor(s): Dennis E Brooks, Irene Rochlitz, David L Williams, James Oliver
Introduction
- Cause: usually spontaneous, exposure to high levels of UV radiation.
- Signs: mass, ocular discharge, 'red eye', ocular discomfort, periocular swelling.
- Diagnosis: clinical examination, cytology, histopathology.
- Treatment: surgical excision, radiotherapy, chemotherapy, plesiotherapy.
- Prognosis: guarded, often malignant.
Pathogenesis
Etiology
- In order of decreasing frequency:
Predisposing factors
General
- Older cats.
- Unpigmented eyelids.
- Sunny climates.
Specific
- High levels of UVB can induce malignant transformation of squamous epithelial cells.
Pathophysiology
- High levels of UVB can induce malignant transformation of squamous epithelial cells.
Timecourse
Diagnosis
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Treatment
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Prevention
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Outcomes
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Further Reading
Publications
Refereed papers
- Recent references from PubMed and VetMedResource.
- Murphy S (2013) Cutaneous squamous cell carcinoma in the cat: current understanding and treatment approaches. J Feline Med Surg 15 (5), 401-407 PubMed.
- Montgomery K W, van der Woerdt A, Aquino S M et al (2010) Periocular cutaneous mast cell tumors in cats: evaluation of surgical excision (33 cases). Vet Ophthalmol 13 (1), 26-30 PubMed.
- Schobert C S, Labelle P, Dubielzig R R (2010) Feline conjunctival melanoma: histopathological characteristics and clinical outcomes. Vet Ophthalmol 13 (1), 43-46 PubMed.
- Newkirk K M, Rohrbach B W (2009) A retrospective study of eyelid tumors from 43 cats. Vet Pathol 46 (5), 916-927 PubMed.
- Aquino S M (2007) Management of eyelid neoplasms in the dog and cat. Clinical techniques in Small Animal Practice 22 (2), 46-54 PubMed.
Other sources of information
- Mitchell N & Oliver J (2015) Feline Ophthalmology - The Manual. Servet. ISBN 978-84-16315-11-6.
- Gould D & McLellan G (2014) BSAVA Manual of Small Animal Ophthalmology. 3rd edn. British Small Animal Veterinary Association.