ISSN 2398-2950      

Leptospira interrogans

ffelis
Contributor(s):

Melissa Kennedy


Introduction

Classification

Taxonomy

  • Order: Spirochaetales.
  • Family: Leptospiraceae.
  • Genus: Leptospira.
  • Species: Leptospira interrogans.
  • More than 180 serovars.

Etymology

  • Greek: spira- a coil; chaete- a hair.

Active Forms

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Clinical Effects

Epidemiology

Habitat

  • Survive in contaminated water.
  • Areas of high rainfall and poor drainage harbor infections.

Lifecycle

  • Long generation time (12 hours).

Transmission

  • Reservoir hosts include rodents. Reservoir hosts become infected with host-adapted serovars.
  • Leptospira spp are found in the mammalian kidney and excreted in the urine. The reservoir host shows none or only mild clinical signs.
  • Direct or indirect - contact with mucous membranes or damaged skin.
  • Indirect - depends on wet conditions.

Pathological effects

  • Antibodies important for clearance.
  • Damage vascular epithelium.
  • Damages parenchymal tissue in organs to which it is disseminated.

Diseases associated with L. interogans

  • Subclinical with L. canicola.
  • Acute hemorrhagic disease, L. icterohemorrhagiae.
  • Less acute icteric type, L. canicola or L. icterohemorrhagiae.
  • Uremia, L. canicola.
  • Chronic hepatitis, L. grippotyphosa.
  • Acute renal failure, L. grippotyphosa.

Control

Control via chemotherapies

Control via environment

  • Prevent contact with urine-contaminated water, especially near rodent habitats.

Vaccination

Diagnosis

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Kalin M, Devaux C, DiFruscia R et al (1999) Three cases of canine leptospirosis in Quebec. Can Vet J 40 (3), 187-191 PubMed.
  • Birnbaum N, Barr S C, Centre S A et al (1998) Naturally acquired leptospirosis in 36 dogs: serological and clinicopathological features. JSAP 39 (5), 231-236 PubMed.
  • Weekes C C, Everard C O & Levett P N (1997) Seroepidemiology of canine leptospirosis on the island of Barbados. Vet Microbiol 57 (2-3), 215-222 PubMed.
  • Rentko V T, Clark N, Ross L A et al (1992) Canine leptospirosis. A retrospective study of 17 cases. JVIM (4), 235-244 PubMed.

Can’t find what you’re looking for?

We have an ever growing content library on Vetlexicon so if you ever find we haven't covered something that you need please fill in the form below and let us know!

 
 
 
 

To show you are not a Bot please can you enter the number showing adjacent to this field

 Security code