Felis ISSN 2398-2950

Aspergillus fumigatus

Synonym(s): A. fumigatus

Contributor(s): Richard Walker

Introduction

Classification

Taxonomy

  • Kingdom: Fungi.
  • Division: Amastogomycota.
  • Order: Eurotiales.
  • Genus: Aspergillus.
  • Species: fumigatus.

Etymology

  • Latin: asperge - sprinkle; fumus - smoke.

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Clinical Effects

Epidemiology

Transmission

  • Inhalation or ingestion from the environment.

Pathological effects

  • Depends on impaired defenses in host to assume pathogenic role.
  • Produces hemolysins, proteolytic enzymes and other toxic factors but their role in pathogenesis is not known.
  • Horses: guttural pouch mycosis, nasal granulomas, intestinal disease in foals.
  • Dogs: otitis externa (often mixed infection), chronic rhinitis (nasal aspergillosis).
  • Cattle: abortion, pneumonia, mastitis, intestinal disease in calves.
  • Birds: pneumonia and respiratory tract infection.
  • Humans: local infection, generalized infection and allergic reactions (often affects immunocompromized patients).
  • Cats: rare, pneumonia Pneumonia.

Other Host Effects

  • Opportunistic pathogen.

Control

Control via chemotherapies

  • Topically: iodine or nystatin Nystatin.
  • Systemically: amphotericin B Amphotericin B, itraconozole Itraconazole (orally).
  • Products not licensed for this use in the cat.

Vaccination

  • Not available.

Diagnosis

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Adamama-Moraitou K K, Paitaki C G, Rallis T S et al (2001) Aspergillus species cystitis in a cat. J Feline Med Surg (3), 31-34 PubMed.
  • Guillot J, Sarfati J, Ribot X et al (1997) Detection of antibodies to Aspergillus fumigatus in serum of horses with mycosis of the auditory tube diverticulum (guttural pouch). Am J Vet Res 58 (12), 1364-1366 PubMed.
  • Clercx C, McEntee K, Snaps F et al (1996) Bronchopulmonary and disseminated granulomatous disease associated with Aspergillus fumigatus and Candida species infection in a golden retriever. JAAHA 32 (2), 139-145 PubMed.
  • Kunkle R A, Rimler R B (1996) Pathology of acute aspergillosis in turkeys. Avian Dis 40 (4), 875-886 PubMed.
  • Sarfati J, Jensen H E, Latgé J P et al (1996) Route of infections in bovine aspergillosis. J Med Vet Mycol 34 (6), 379-383 PubMed.

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