ISSN 2398-2985      

Clotrimazole

Jreptile

Synonym(s): Canesten, Lotriderm, Mycelex, Lotrimin


Introduction

Name

  • Clotrimazole.

Class of drug

  • Synthetic broad-spectrum imidazole antifungal.

Description

Chemical name

  • 1-[(2-chlorophenyl)diphenylmethyl]-1H-imidazole.
  • 1-(o-chloro-alpha,alpha-diphenylbenzyl)imidazole.

Molecular formula

  • C22H17ClN2.

Molecular weight

  • 344.84.

Physical properties

  • Odorless, white crystalline powder, insoluble in water and soluble in ethanol.

Storage requirements

  • <25°C/77°F.

Uses

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Indications

  • Dermal fungal infections .
  • Superficial yeast infections: Malassezia and Candida.
  • Also active against superficial infections with Aspergillus spp.

Administration

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Pharmacokinetics

Precautions

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Adverse Reactions

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Further Reading

Publications

Refereed papers

Other sources of information

  • Meredith A (2015) Ed. Small Animal Formulary. Part B: Exotic Pets. 9th edn. BSAVA, UK.
  • Girling S J & Raiti P (2004) BSAVA Manual of Reptiles. BSAVA, UK. pp 383.

Organisation(s)

  • National Office of Animal Health (NOAH) Compendium of Data Sheets for Animal Medicines. Website: www.noahcompendium.co.uk.

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