ISSN 2398-2985      

Blood biochemistry: creatinine

6guinea pig
Contributor(s):

Vetstream Ltd

Molly Varga

Synonym(s): Serum creatinine


Overview

  • Derived from breakdown of creatine in muscle.
  • Excreted by kidneys.
  • Not influenced by protein metabolism (unlike urea), diet or hydration.
  • Important marker of renal function; levels controlled by excretion rate, but relatively insensitive.
  • Clearance is identical to inulin and therefore accurately measures glomerular filtration rate.

Sampling

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Tests

Availability

  • Widely available.

Technique (intrinsic) limitations

  • Interpret in conjunction with other laboratory and clinical findings.

Result Data

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Benson K G & Paul-Murphy J (1999) Clinical pathology of the domestic rabbit: acquisition and interpretation of samples. Vet Clin North Am Exotic Anim Pract 2 (3), 539-552 PubMed.

Other sources of information

  • Varga M (2014) Textbook of Rabbit Medicine. 2nd edn. Butterworth Heinemann Elsevier, UK.
  • Wesche P (2014) Clinical Pathology. In: BSAVA Manual of Rabbit Medicine.Eds: Meredith A & Lord B. BSAVA, UK. pp 124-137.
  • Harcourt-Brown F (2013) Diagnosis of Renal Disease in Rabbits. Vet Clin North Am Exotic Anim Pract 16, 145-174.
  • Krause A L, Weisbroth S H, Flatt R E & Brewer N (1984) Biology and Diseases of Rabbits. In: Laboratory Animal Medicine.Eds: Fox J G, Cohen B J S & Loew F M. Academic Press, USA. pp 207-240.

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