ISSN 2398-2985      

Tropicamide

6guinea pig

Synonym(s): Mydriacyl, Minims Tropicamide


Introduction

Name

  • Tropicamide.

Class of drug

  • Anticholinergic.

Description

Chemical name

  • Tropicamide.
  • (2RS)N-ethyl-3-hydroxy-2-phenyl-N-(prid-4-ylmethyl)propionamide.

Molecular formula

  • C17H20N2O2.

Molecular weight

  • 284.35.

Physical properties

  • Clear, colorless sterile ophthalmic solution.
  • 0.5% (5 mg/ml) or 1% (10 mg/ml) concentrations available.

Storage requirements

  • Store below 25°C/77°F and do not freeze or refrigerate.
  • Protect from light.
  • To reduce risk of bottle contamination, do not touch dropper bottle to ocular surface during application.
  • Discard drops within 28 days of opening.
  • Single-use vials available.

Uses

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Indications

  • Topical mydriatic and cyclopegic.
  • Ophthalmic examination (particularly of the fundus).

Administration

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Pharmacokinetics

Precautions

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Interactions

with other drugs

  • Potential interactions with concomitant use of other antimuscarinic drugs, eg some antihistamines.

with diagnostic tests

  • Unable to assess iris after mydriasis performed.

Adverse Reactions

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Further Reading

Publications

Refereed papers

Other sources of information

  • Product Information (2017) Mydriacyl ® (Tropicamide) 0.5% and 1.0% Eye Drops. In: Medsafe - New Zealand Medicines and Medical Devices Safety Authority. Website: www.medsafe.govt.nz. Last accessed 6th April 2017.
  • Meredith A (2015) Ed. BSAVA Small Animal Formulary. Part B: Exotic Pts. 9th edn. BSAVA, UK. pp 338.
  • Harkness J E & Wagner J E (1995) The Biology and Medicine of Rabbits and Rodents. 4th edn. Williams & Wilkins, Media, PA.

Organisation(s)

  • National Office of Animal Health (NOAH) Compendium of Data Sheets for Animal Medicines. Website: www.noahcompendium.co.uk.

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