ISSN 2398-2985      

Flumazenil

6guinea pig

Synonym(s): Flumazenilum, Flumazepil, Romazicon, Flumazen, Anexate, Lanexat, Flumage


Introduction

Name

  • Flumazenil.

Class of drug

  • Benzodiazepine anatagonist.

Description

Chemical name

  • •Ethyl 8-fluoro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a](1,4) benzodiazepine-3-carboxylate.

Molecular formula

  • •C15H14FN3O3.

Molecular weight

  • •303.3.

Physical properties

  • •White to off-white crystalline compound, insoluble in water but soluble in acidic aqueous solutions.

Storage requirements

  • •Once drawn into a syringe or mixed with solutions, discard after 24 h.

Uses

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Indications

  • Reversal of benzodiazepine effects after either therapeutic use or overdosages.

Administration

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Pharmacokinetics

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Precautions

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Adverse Reactions

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Further Reading

Publications

Other sources of information

  • Plumb D (2015) Plumb’s Veterinary Drug Handbook. 8th edn. Wiley Blackwell. pp 1296.
  • Hawkins M G & Pascoe P J (2012) Anesthesia, analgesia, and sedation of small mammals. In: Ferrets, Rabbits, and Rodents: Clinical Medicine and Surgery. 3rd edn. Eds: Quesenberry K E, Carpenter J W. Elsevier, USA. pp 429-451.

Organisation(s)

  • National Office of Animal Health (NOAH) Compendium of Data Sheets for Animal Medicines. Website: www.noahcompendium.co.uk.
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