ISSN 2398-2985      

Deslorelin

6guinea pig

Synonym(s): Suprelorin


Introduction

Name

  • Deslorelin.
  • Available veterinary formulation contains deslorelin as deslorelin acetate.

Class of drug

  • Gonadotrophin-releasing hormone (GnRH) agonist.

Description

Molecular formula

  • C64H83N17O12.

Molecular weight

  • 1282.45 g/mol

Physical properties

  • White to pale yellow cylindrical implant (size of a microchip).
  • Implant is supplied in a pre-loaded implanter.

Storage requirements

  • Store in refrigerator (2-8°C/35.6-46.4°F).
  • Do not freeze.
  • Shelf-life of product packaged for sale: 2 years.

Uses

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Indications

  • Used to suppress sexual behaviour and prevent pregnancy in dogs, cats and ferrets.
  • Used in the treatment of adrenal disease in ferrets.
  • Anecdotally useful for some types of cystic ovarian disease Cystic ovarian disease in guinea pigs duration of action is uncertain.

Administration

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Pharmacokinetics

Precautions

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Interactions

with other drugs

  • None known.
Warnings for personnel handling the product
  • Women in childbearing age should avoid contact with the product or wear disposable plastic gloves when handling the product.
  • ​Pregnant women should handle the product with extreme care.

Adverse Reactions

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Kohutova S, Jekl V, Knotek Z & Hauptman K (2015) The effect of deslorelin acetate on the oestrous cycle of female guinea pigs. Vet Med 60 (3), 155-160 VetMedResource.
  • Pilny A (2014) Ovarian cystic disease in guinea pigs. Vet Clin North Am Exot Anim Pract 17 (1), 69-75 PubMed.

Organisation(s)

  • National Office of Animal Health (NOAH) Compendium of Data Sheets for Animal Medicines. Website: www.noahcompendium.co.uk.

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