ISSN 2398-2985      

Colestyramine

6guinea pig

Synonym(s): Cholestyramine


Introduction

Class of drug

  • Ion exchange resin.

Description

Chemical name

  • [4-[3-(4-ethylphenyl)butyl]phenyl]-trimethylazanium;chloride.

Molecular formula

  • C21H30ClN.

Molecular weight

  • 331.928 g/mol.

Uses

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Indications

  • Enterotoxemia Diarrhea (Clostridia spp overgrowth) which may occur as a result of:
    • Alterations in cecal pH if excessive carbohydrates are fed.
    • Falling fiber content of diet.
    • Excess dietary protein.
    • Antibiotic administration.
    • Stress of any kind resulting in reduction in gut motility.

Administration

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Pharmacokinetics

Adverse Reactions

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • ​Lipman N S, Weischedel A K, Conner M J, Olsen D A & Taylor N S (1992) Utilization of chlorstyramine resin as a preventative treatment for antibiotic (clindamycin)-induced enterotoxemia in the rabbit. Lab Anim 26 (1), 1-8 PubMed.

Other sources of information

  • Meredith A (2015) Ed Small Animal Formulary. Part B: Exotic Pets.  9th edn. BSAVA, UK.
  • Keeble E & Meredith A (2009) Eds. Manual of Rodents and Ferrets. BSAVA, Quedgeley, Gloucester.

Organisation(s)

  • National Office of Animal Health (NOAH) Compendium of Data Sheets for Animal Medicines. Website: www.noahcompendium.co.uk.

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