ISSN 2398-2985      

Azithromycin

6guinea pig
Contributor(s):

Vetstream Ltd

Mark Naguib


Introduction

Name

  • Azithromycin.

Uses

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Indications

  • As broad spectrum antibacterial for consideration when safer alternatives have proved ineffective
  • In situations where penicillins might be considered in other species, but where the risks of penicillin use in guinea pigs prevent their use.
  • To assist in the management of abscesses, since it is particularly effective against the commonly associated bacteria (Pasteurella, Staphyloccocus, anaerobes). 
  • Management of respiratory tract infections.
  • Management of mild to moderate skin and soft tissue infection.
  • Treatment of non-tubercular mycobacterial infections.
  • In man is used as a single dose for treatment of genital chlamydial infections.
  • Active against gram positive cocci (except some Staphylococci), gram positive bacilli, some gram negative bacilli, (such as Haemophilus and Pasteurella spp).
  • Also effective against:
    • Mycobacteria.
    • Anaerobes.
    • Chlamydia spp.
    • Mycoplasma spp.
    • Toxoplasma spp.
  • Some strains of Actinomyes, Nocardia, Chlamydia, and Rickettsia are inhibited by azithromycin.
  • Resistance is exhibited by most strains of Pseudomonas spp, E. coli and Klebsiella.

Administration

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Pharmacokinetics

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Precautions

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Interactions

with other drugs

  • Increases serum levels of:

Adverse Reactions

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Jenkins J R (2010) Diseases of Geriatric Guinea Pigs and Chinchillas. Veterinary Clinics of North America: Exotic Animal Practice, 13 (1), 85-93 PubMed.

Other sources of information

  • Quesenberry K E & Carpenter J W (2004) Formulary. In: Ferrets, Rabbits and Rodents: Clinical Medicine and Surgery. 2nd edn. pp 436-444.

Organisation(s)

  • National Office of Animal Health (NOAH) Compendium of Data Sheets for Animal Medicines. Website: www.noahcompendium.co.uk.
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