ISSN 2398-2985      

Sebaceous adenoma

6guinea pig
Contributor(s):

Cathy Johnson-Delaney

Synonym(s): Sebaceous hyperplasia, Sebaceous epithelioma, Sebaceous carcinoma, Sebaceous gland hyperplasia/neoplasia


Introduction

  • Cause: a benign neoplasia of a sebaceous gland. It has not been described as starting with an adenitis as it has in rabbits.
  • Signs: skin becomes raised, non-pruritic scaling, with some flaking and alopecia; usually localized and slow-growing; hair loss.
  • Diagnosis: excision with histopathology. Other skin lesions may look similar.
  • Treatment: excision is usually curative.
  • Prognosis: good. May have others develop.

Pathogenesis

Etiology

  • Not listed specifically for guinea pigs.
  • In rabbits, sebaceous adenomas may develop following adenitis, which is considered an autoimmune disease.

Pathophysiology

  • Normal sebaceous gland tissue is replaced by neoplastic tissue including hyperkeratosis, follicular keratosis and dystrophy, and fibrosis.

Timecourse

  • Likely slow, although exact timing for development is not published.

Epidemiology

  • Individual problem.

Diagnosis

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Treatment

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Outcomes

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Further Reading

Publications

Refereed papers

Other sources of information

  • Kanifer S & Reavill D R (2013) Cutaneous neoplasia in ferrets, rabbits, and guinea pigs. Vet Clin Exot Anim 15 (3), 579-598 PubMed.
  • Percy D H & Barthold S W (2007) Guinea Pigs. In: Pathology of Laboratory Rodents and Rabbits. 3rd edn. Eds: Percy D H & Barthold S W. Blackwell Publishing. pp 217-251.

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