ISSN 2398-2985      

Pseudotuberculosis

6guinea pig

Synonym(s): Yersinia infection


Introduction

  • Cause: infection with Yersinia pseudotuberculosis, a gram-negative bacterium.
  • Signs: weight loss, diarrhea, cervical lymphadenopathy, gradual loss of condition, eventual death. There are non-fatal infections which are limited to the cervical lymph nodes.
  • Diagnosis: identification of organisms from lymph node aspirate or blood culture (if septicemic).
  • Treatment: usually euthanasia as this is considered zoonotic and of public health significance, particularly to immunocompromised people.
  • Prognosis: poor, even if non-fatal presentation due to zoonotic potential.

Pathogenesis

Etiology

  • Ingestion primarily, from contaminated bedding or food with Yersinia pseudotuberculosis carried by wild rodents or birds.

Predisposing factors

General

  • Premises, food/bedding storage can be contaminated by wild rodents, birds.

Specific

  • Any stress condition: especially poor diet, sanitation.
  • Vitamin C deficiency Vitamin C deficiency with secondary immunosuppression.

Pathophysiology

  • May become septicemic: usually die.
  • Non-fatal infections concentrated in cervical lymph nodes.
  • Most cases are gradual declination of health resulting in death (several weeks of illness).

Timecourse

  • Several weeks.

Epidemiology

  • Usually ingestion from contaminated food, bedding.
  • Potentially transmissible between individuals: if cervical lymph nodes ulcerate, infected material may contaminate bedding, food.

Diagnosis

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Treatment

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Prevention

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Outcomes

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Further Reading

Publications

Refereed papers

Other sources of information

  • Johnson-Delaney C (2010) Guinea Pigs, Chinchillas, Degus and Duprasi. In: BSAVA Manual of Exotic Pets. 5th edn. Eds: Meredith A & Johnson-Delaney C. British Small Animal Veterinary Association. pp 28-62.
  • Percy D H & Barthold S W (2007) Guinea Pigs. In: Pathology of Laboratory Rodents and Rabbits. 3rd edn. Eds: Percy D H & Barthold S W. Blackwell Publishing. pp 217-251.

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