ISSN 2398-2985      

Mammary gland adenocarcinoma

6guinea pig

Synonym(s): Mammary gland neoplasia, Mammary tumor


Introduction

  • Cause: mammary tumors are under estrogen and progesterone stimulation.
  • Signs: small nodule in glandular tissue -> ulcerated. May be serous or bloody discharge.
  • Diagnosis: fine needle aspirate. Material collected can be cultured if bacterial infection suspected -> cytology. Biopsy for histopathology.
  • Treatment: surgical excision is curative for most.
  • Prognosis: generally guarded.

Pathogenesis

Etiology

  • Unknown.

Predisposing factors

General

  • Mammary gland tumors occur in both male and female guinea pigs, both intact and castrated/ovariohysterectomized.

Pathophysiology

  • It is proposed that there may be reproductive hormone stimulation that induces neoplasia.

Timecourse

  • Usually weeks to months.

Epidemiology

  • Not a contagious process.

Diagnosis

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Treatment

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Outcomes

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Further Reading

Publications

Refereed Papers

  • Recent references from PubMed and VetMedResource.
  • Kanfer S & Reavill D R (2013) Cutaneous neoplasia in ferrets, rabbits, and guinea pigs. Vet Clin Exot Anim 16 (3), 579-598 PubMed.
  • Suarez-Bonnet A, Martin de las Mulas J, Millan M Y et al (2010) Morphological and immunohistochemical characterization of spontaneous mammary gland tumors in the guinea pig (Cavia porcellus). Vet Pathol 47 (2), 298–305 PubMed.

Other sources of information

  • Hawkins M G & Bishop C R (2012) Disease Problems of Guinea Pigs. In: Ferrets, Rabbits, and Rodents Clinical Medicine and Surgery. 3rd edn. Eds: Quesenberry K E & Carpenter J W. Elsevier. pp 295-310.
  • Percy D H & Barthold S W (2007) Guinea Pigs. In: Pathology of Laboratory Rodents and Rabbits. 3rd edn. Eds: Percy D H & Barthold S W. Blackwell Publishing. pp 217-251.

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