ISSN 2398-2985      

Hyperglycemia

6guinea pig

Synonym(s): High blood glucose (blood sugar)


Introduction

  • Cause: insulin deficiency (diabetes mellitus), insulin resistance, stress, neoplasia, metabolic disease, iatrogenic, drug use in certain species.
  • Signs: polyuria, polydipsia, lethargy, polyphagia, weight loss, cataracts, neurological signs if severe.
  • Diagnosis: blood glucose measurement, urinalysis, investigation of underlying cause.
  • Treatment: insulin therapy, diet change, treat underlying cause.
  • Prognosis: variable depending on cause.

Pathogenesis

Etiology

  • Spontaneous diabetes mellitus Diabetes mellitus is described in laboratory guinea pigs but is rare in pet guinea pigs. 
  • Secondary to obesity Obesity (insulin resistance).
  • Liver disease.
  • Drug use (corticosteroids).
  • Stress.

Predisposing factors

General

Epidemiology

  • Rarely reported.

Diagnosis

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Treatment

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Prevention

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Outcomes

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Further Reading

Publications

Refereed Papers

Other sources of information

  • Hawkins M G & Bishop C R (2012) Disease Problems of Guinea Pigs. In: Ferrets, Rabbits, and Rodents. 3rd edn. Eds: Quesenberry K E & and Carpenter J W. W B Saunders, USA. pp 295-310.
  • Rosenthal K L & Wyre N R (2012) Endocrine Diseases. In: Ferrets, Rabbits, and Rodents. 3rd edn. Eds: Quesenberry K E & Carpenter J W. W B Saunders, USA. pp 86-102.
  • Orr H (2009) Rodents: Neoplastic and Endocrine Disease. In: BSAVA Manual of Rodents and Ferrets. Eds: Keeble E & Meredith A. British Small Animal Veterinary Association, UK. pp 181-192.

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