ISSN 2398-2985      

Glucosuria

6guinea pig

Synonym(s): Glycosuria, Glucose in the urine


Introduction

  • Cause: glucose present in the urine. Represents glucose over the renal threshold for filtration from the blood. Can be seen with high blood glucose, bacterial cystitis; stressed guinea pigs may have transient glucosuria. Other less common causes of glucosuria are primary renal tubular problems.
  • Signs: may notice polyuria, polydipsia. If cystitis may be urinating frequently, small amounts. May be asymptomatic.
  • Diagnosis: urine sample best obtained from cystocentesis. Full urinalysis including culture to rule out cystitis. Bloodwork: serum chemistries including glucose, preferably glucose measured immediately in an in-house chemistry system to evaluate blood glucose level accurately. Radiography, ultrasonography.
  • Treatment: depends on cause.
  • Prognosis: depends on cause.

Pathogenesis

Etiology

  • For cystitis Cystitis/urolithiasis Urolithiasis, may be ascending bacterial infection.
  • Mild dehydration and/or not enough fluid intake may predispose.
  • For diabetes mellitus Diabetes mellitus, may be associated with obesity, diet high in calories with relatively low fiber.
  • Stress can cause glucosuria in guinea pigs.

Predisposing factors

General

Specific

  • Stress (often husbandry, dietary, social, etc).

Timecourse

  • Relatively rapid for cystitis/urolithiasis.
  • May be slowly progressive if diabetes.

Epidemiology

  • Individual guinea pig problem.

Diagnosis

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Treatment

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Prevention

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Outcomes

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Further Reading

Publications

Refereed Papers

Other sources of information

  • Hawkins M G & Bishop C R (2012) Disease Problems of Guinea Pigs. In: Ferrets, Rabbits, and Rodents Clinical Medicine and Surgery. 3rd edn. Eds: Quesenberry K E & Carpenter J W. Elsevier. pp 295-310.
  • Bishop C R, Fischer J, Brossoit A, Pierson C (2010) Standardization of renal physiology parameters in guinea pigs via urinalysis. Proc Annu Conf Assoc Avian Vet, Assoc Exot Mamm Vet. pp 49-52.

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