ISSN 2398-2977      

Sodium bicarbonate

pequis
Contributor(s):

Mark Senior

Synonym(s): Bicarbonate of Soda


Introduction

Name

  • Sodium bicarbonate.

Class of drug

  • Alkalinizer.

Description

Chemical name

  • Sodium bicarbonate.

Molecular formula

  • NaHCO3.

Uses

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Indications

  • Treatment of metabolic acidosis.
  • As an adjunctive therapy in the treatment of hypercalcemic or hyperkalemic crises.

Administration

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Pharmacokinetics

Precautions

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Interactions

with other drugs

Many drugs
  • Sodium bicarbonate is incompatible with many drugs - do not mix until checked.

Dogs and cats

Calcium salts

  • Sodium bicarbonate is incompatible with calcium salts.

Quinidine

  • Alkalinization of urine with sodium bicarbonate decreases the excretion of quinidine   Quinidine  .

Sympathomimetic drugs

  • Alkalinization of urine with sodium bicarbonate decreases the excretion of sympathomimetic drugs.

Aspirin

  • Alkalinization of urine with sodium bicarbonate increases the excretion of aspirin   Acetylsalicylic acid  .

Phenobarbital

  • Alkalinization of urine with sodium bicarbonate increases the excretion of phenobarbital   Phenobarbital  .

Tetracyclines

  • Alkalinization of urine with sodium bicarbonate increases the excretion of tetracyclines, especially doxycycline.

Adverse Reactions

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Further Reading

Publications

Refereed papers

Other sources of information

  • Derived from The Small Animal Formulary (1999) 3rd edn. Ed: Tennant B. British Small Animal Veterinary Association.
  • Derived from The Veterinary Formulary (1998) 4th edn. Ed: Bishop Y. British Veterinary Association and Royal Pharmaceutical Society.
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