ISSN 2398-2977      

Therapeutics: urinary system

pequis

Synonym(s): Therapeutics: renal system


Introduction

  • When renal function is compromised treatment is aimed at increasing urine output by direct action on the glomeruli, and increasing renal blood flow (RBF) and glomerular filtration rate (GFR).
  • This is particularly important in acute renal failure   Kidney: renal failure  .
  • Drugs affecting urine output are:
    • Diuretics.
    • Xanthines.
    • Dopamine.
  • Antidiuretics are used in the diagnosis and management of polyuria   Polydipsia / polyuria  .
  • Drugs which have an effect on the autonomic nervous system and certain reproductive hormone preparations may influence the ability to urinate by having an effect on the detrusor muscle, the urinary outflow tract or the urinary sphincter.
  • Antimicrobials are employed to treat urinary tract infections. Certain antimicrobial groups are particularly well suited to the treatment of infection at this anatomical location.
  • In some situations it may be desirable to use drugs to alter urinary pH.

Diuretics

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Xanthines and dopamine

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Antidiuretics and autonomic stimulating drugs

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Hormones

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Urinary acidifiers and antimicrobials

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Further Reading

Publications

Refereed papers

Other sources of information

  • Bertone J & Horspool L (2004) Eds. Equine Clinical Pharmacology. Saunders. ISBN: 0702024848.
  • Derived from The Veterinary Formula. (2004) 6th edn. Ed: Bishop Y. British Veterinary Association and Royal Pharmaceutical Society. ISBN: 0853695792.
  • Prescott J F, Baggot J D & Walker R D (2000) Eds. Antimicrobial Therapy in Veterinary Medicine. 3rd edn. Iowa State University Press.

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